Mike Evans ruled out, Trent Williams questionable as NFC-leading 49ers' injury concerns persist

The San Francisco 49ers will be without wide receiver Mike Evans for a third consecutive game due to Achilles tendinitis, and left tackle Trent Williams is questionable with a shoulder injury. Despite these concerns, Deebo Samuel is returning from a hamstring injury, and Keenan Allen will make his debut, bolstering the receiver position. The 49ers, holding an NFC-best 7-1 record, also have cornerbacks Deommodore Lenoir and Renardo Green limited in practice, linebacker Dre Greenlaw questionable with a knee injury, and other defensive players listed as questionable.

• Mike Evans has been ruled out for a third straight game with Achilles tendinitis.
• Trent Williams is questionable for Sunday’s game with a shoulder injury.
• Deebo Samuel is set to return after missing three games with a hamstring injury.
• Keenan Allen will make his debut for the 49ers after being acquired in a trade.
• Cornerbacks Deommodore Lenoir and Renardo Green were limited participants after injuries.
• Linebacker Dre Greenlaw is questionable with a knee injury.
• The 49ers currently hold a 7-1 record, leading the NFC.